I can relate to this totally:
Two men in their late forties, were having a drink together, discussing the deleterious effects aging has had on each of them.
The first said, "You know, I can handle the eye-sight going, and the loss of hair, but it's the disconnect between the brain and the mouth that's the worst part for me. For example, just the other day, I was in line to buy an airline ticket. The woman behind the counter was very well-endowed, and as I walked up to her, I blithely announced, 'I would like to buy a picket to Tittsburgh.' God, I was absolutely mortified!"
The second man, shaking his head back and forth, in a been-there-done-that sort of manner said, "I had a very similar experience. I was sitting across from my wife at breakfast one morning, and intended to say, Honey, please pass the Special K.' Instead, it came out, Bitch, you've ruined my life.'"